diff --git a/editor/editor_settings.cpp b/editor/editor_settings.cpp
index 207acb42b5a..fc2b36d2e32 100644
--- a/editor/editor_settings.cpp
+++ b/editor/editor_settings.cpp
@@ -444,6 +444,7 @@ void EditorSettings::_load_defaults(Ref<ConfigFile> p_extra_config) {
 	_initial_set("text_editor/navigation/show_minimap", true);
 	_initial_set("text_editor/navigation/minimap_width", 80);
 	hints["text_editor/navigation/minimap_width"] = PropertyInfo(Variant::INT, "text_editor/navigation/minimap_width", PROPERTY_HINT_RANGE, "50,250,1");
+	_initial_set("text_editor/navigation/mouse_extra_buttons_navigate_history", true);
 
 	// Appearance
 	_initial_set("text_editor/appearance/show_line_numbers", true);
diff --git a/editor/plugins/script_editor_plugin.cpp b/editor/plugins/script_editor_plugin.cpp
index 75e81deff7f..8833f4e8fcb 100644
--- a/editor/plugins/script_editor_plugin.cpp
+++ b/editor/plugins/script_editor_plugin.cpp
@@ -2543,6 +2543,27 @@ void ScriptEditor::drop_data_fw(const Point2 &p_point, const Variant &p_data, Co
 	}
 }
 
+void ScriptEditor::_input(const Ref<InputEvent> &p_event) {
+	// This feature can be disabled to avoid interfering with other uses of the additional
+	// mouse buttons, such as push-to-talk in a VoIP program.
+	if (EDITOR_GET("text_editor/navigation/mouse_extra_buttons_navigate_history")) {
+		const Ref<InputEventMouseButton> mb = p_event;
+
+		// Navigate the script history using additional mouse buttons present on some mice.
+		// This must be hardcoded as the editor shortcuts dialog doesn't allow assigning
+		// more than one shortcut per action.
+		if (mb.is_valid() && mb->is_pressed() && is_visible_in_tree() && !get_viewport()->gui_has_modal_stack()) {
+			if (mb->get_button_index() == BUTTON_XBUTTON1) {
+				_history_back();
+			}
+
+			if (mb->get_button_index() == BUTTON_XBUTTON2) {
+				_history_forward();
+			}
+		}
+	}
+}
+
 void ScriptEditor::_unhandled_input(const Ref<InputEvent> &p_event) {
 	ERR_FAIL_COND(p_event.is_null());
 
@@ -3082,6 +3103,7 @@ void ScriptEditor::_bind_methods() {
 	ClassDB::bind_method("_history_forward", &ScriptEditor::_history_forward);
 	ClassDB::bind_method("_history_back", &ScriptEditor::_history_back);
 	ClassDB::bind_method("_live_auto_reload_running_scripts", &ScriptEditor::_live_auto_reload_running_scripts);
+	ClassDB::bind_method("_input", &ScriptEditor::_input);
 	ClassDB::bind_method("_unhandled_input", &ScriptEditor::_unhandled_input);
 	ClassDB::bind_method("_script_list_gui_input", &ScriptEditor::_script_list_gui_input);
 	ClassDB::bind_method("_toggle_members_overview_alpha_sort", &ScriptEditor::_toggle_members_overview_alpha_sort);
@@ -3211,8 +3233,10 @@ ScriptEditor::ScriptEditor(EditorNode *p_editor) {
 	ED_SHORTCUT("script_editor/window_sort", TTR("Sort"));
 	ED_SHORTCUT("script_editor/window_move_up", TTR("Move Up"), KEY_MASK_SHIFT | KEY_MASK_ALT | KEY_UP);
 	ED_SHORTCUT("script_editor/window_move_down", TTR("Move Down"), KEY_MASK_SHIFT | KEY_MASK_ALT | KEY_DOWN);
-	ED_SHORTCUT("script_editor/next_script", TTR("Next script"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_PERIOD); // these should be KEY_GREATER and KEY_LESS but those don't work
-	ED_SHORTCUT("script_editor/prev_script", TTR("Previous script"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_COMMA);
+	// FIXME: These should be `KEY_GREATER` and `KEY_LESS` but those don't work.
+	ED_SHORTCUT("script_editor/next_script", TTR("Next Script"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_PERIOD);
+	ED_SHORTCUT("script_editor/prev_script", TTR("Previous Script"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_COMMA);
+	set_process_input(true);
 	set_process_unhandled_input(true);
 
 	file_menu = memnew(MenuButton);
diff --git a/editor/plugins/script_editor_plugin.h b/editor/plugins/script_editor_plugin.h
index 27843baa29e..440d49b2213 100644
--- a/editor/plugins/script_editor_plugin.h
+++ b/editor/plugins/script_editor_plugin.h
@@ -369,6 +369,7 @@ class ScriptEditor : public PanelContainer {
 	bool can_drop_data_fw(const Point2 &p_point, const Variant &p_data, Control *p_from) const;
 	void drop_data_fw(const Point2 &p_point, const Variant &p_data, Control *p_from);
 
+	void _input(const Ref<InputEvent> &p_event);
 	void _unhandled_input(const Ref<InputEvent> &p_event);
 
 	void _script_list_gui_input(const Ref<InputEvent> &ev);